physicians in New Mexico notified the New Mexico Department of Health and Environment of 3 patients with marked eosinophilia and severe. incapacitating myalgia who had been taking the amino acid L-tryptophan (orally) and whose illness, after thorough clinical evaluation, seemed both unusual and obsc
Continuing scientific concerns about the validity of the l-tryptophan eosinophilia-myalgia syndrome association
✍ Scribed by Stephen R. Daniels; James I. Hudson; Ralph I. Horwitz
- Book ID
- 116154987
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 410 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0895-4356
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## Abstract ## Objective To assess L‐tryptophan (LT) dose, age, sex, and immunogenetic markers as possible risk or protective factors for the development of LT‐associated eosinophilia–myalgia syndrome (EMS) and related clinical findings. ## Methods HLA–DRB1 and DQA1 allele typing and Gm/Km pheno