Continued in vitro and in vivo release of an antitumor drug from albumin microspheres
β Scribed by S. Fujimoto; F. Endoh; Y. Kitsukawa; K. Okui; Y. Morimoto; K. Sugibayashi; A. Miyakawa; H. Suzuki
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 543 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1420-682X
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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable polyβlacticβ__co__βglycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr
acrylic copolymer entrapment product containing 25 % drug, is quite different. The diffraction pattern indicates that crystalline drug is absent. The absence of crystalline drug in this sample demonstrates that the drug in the entrapment product is uniformly dispersed at a molecular level. The mech