Continuation and long-term maintenance treatment with Hypericum extract WS® 5570 after recovery from an acute episode of moderate depression — A double-blind, randomized, placebo controlled long-term trial

Continuation and long-term maintenance t

Continuation and long-term maintenance treatment with Hypericum extract WS® 5570 after successful acute treatment of mild to moderate depression – rationale and study design

✍ S. Kasper; A. Dienel; M. Kieser 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB

## Abstract Unipolar major depression is often a chronic disease that may require lifelong prophylaxis. Recovery from an acute episode is followed by 4‐6 months of relapse prevention. After that, long‐term maintenance treatment is administered to avoid recurrence. We present the rationale and desi