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Context-specific modulation of cocaine-induced locomotor sensitization and ERK and CREB phosphorylation in the rat nucleus accumbens

โœ Scribed by Marcelo T. Marin; Alexander Berkow; Sam A. Golden; Eisuke Koya; Cleopatra S. Planeta; Bruce T. Hope


Book ID
109028035
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
492 KB
Volume
30
Category
Article
ISSN
0953-816X

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## Abstract The nucleus accumbens region of the brain has been shown to play a role in reward and reinforcing mechanisms of drugs of abuse. To understand the molecular mechanisms of nicotine addiction, the present investigation examined the effects of acute and chronic nicotine treatment and its wi