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Contamination of Mesenchymal Stem-Cells with Fibroblasts Accelerates Neurodegeneration in an Experimental Model of Parkinson’s Disease

✍ Scribed by Marcia C. L. Pereira; Mariane Secco; Daniela E. Suzuki; Luciana Janjoppi; Carolina O. Rodini; Layla B. Torres; Bruno H. S. Araújo; Esper A. Cavalheiro; Mayana Zatz; Oswaldo Keith Okamoto

Book ID
107568229
Publisher
Humana Press Inc
Year
2011
Tongue
English
Weight
905 KB
Volume
7
Category
Article
ISSN
1550-8943

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## Abstract Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive degeneration of nigrostriatal dopaminergic (DA) neurons. The therapeutic potential of glial cell line‐derived neurotrophic factor (GDNF), the most potent neurotrophic factor for DA neurons, has been dem