Contact allergies to metal components of the 316 L steel in patients with coronary heart disease
✍ Scribed by U. Hillen; M. Haude; R. Erbel; M. Goos
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 62 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0933-5137
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✦ Synopsis
Abstract
In‐stent restenosis is a complication which impairs the success of coronary stenting. Recently it was supposed that a delayed hypersensitivity reaction to nickel and molybdenum might be one of the triggering factors in in‐stent restenosis. We have performed a retrospective analysis of the data collected in our centre with respect to this hypothesis. Altogether 20 patients were investigated (13 male, 7 female). Patch tests were performed with the standard series of the German Contact Dermatitis Research Group and a metal series containing the metal components of the 316 L stainless steel. A positive patch test reaction to nickel was observed in 2 (10.0%) patients, one of these patients had an in‐stent restenosis, the other had not. None of the patients showed a sensitization to the other metals. Restenoses were predominantly observed in patients with a negative patch test reaction to nickel (6/18 patients). Although it cannot be excluded that metal allergy may play a role in the restenosis process in coronary stenting there is at the moment little evidence for it.