Contributions of contact activation path
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Kaushik Chatterjee; Zhe Guo; Erwin A. Vogler; Christopher A. Siedlecki
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Article
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2009
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John Wiley and Sons
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English
β 276 KB
## Abstract Activation of human blood plasma coagulation by contact with hydrophilic or hydrophobic surfaces (procoagulants) is dominated by kallikrein (Kal)βmediated activation of the blood zymogen FXII (Hageman Factor). Mathematical modeling of prekallikrein (PK)βdeficient plateletβpoor plasma (d