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Construction of Substituted N-Hydroxyindoles: Synthesis of a Nocathiacin I Model System

โœ Scribed by K. C. Nicolaou; Sang Hyup Lee; Anthony A. Estrada; Mark Zak


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
372 KB
Volume
117
Category
Article
ISSN
0044-8249

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Total Synthesis of Brevetoxin A: Part 2:
โœ K. C. Nicolaou; Paul A. Wallace; Shuhao Shi; Michael A. Ouellette; Mark E. Bunna ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 252 KB ๐Ÿ‘ 2 views

Our second generation strategy for the total synthesis of brevetoxin A involved dissection of the molecule at the ring F oxocene. Synthetically, the F ring formation was expected to occur through Wittig coupling of requisite polycyclic fragments 2 and 3, followed by a hydroxy dithioketal cyclization