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Construction of SHIVs expressing quaternary neutralization epitopes in Env and mimicking the neutralization phenotype of typical HIV-1 isolates

✍ Scribed by JF Theis, A de Parseval, WJ Honnen, A Phogat, UC Ganapathi, Z Lai, L Peng…

Book ID: 120691349
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 66 KB
Volume: 9
Category: Article
ISSN: 1742-4690
DOI: 10.1186/1742-4690-9-S2-P28

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## Abstract The hypothesis is that there are neutralizing epitopes on the surface of free virions of human immunodeficiency virus type 1 (HIV‐1) that correspond to the genetic subtype of the envelope glycoprotein. Assays with extended incubation and reduced absorption phases are required to demonst