Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH–cytochrome P450 reductase
✍ Scribed by Ken-ichi Fujita; Kazuo Nakayama; Yoshiyuki Yamazaki; Kazuhiro Tsuruma; Masami Yamada; Takehiko Nohmi; Tetsuya Kamataki
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 135 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.10034
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep
To establish a prediction system for drug-induced gynecomastia in clinical fields, a model reaction system was developed to explain numerically this side effect. The principle is based on the assumption that 50% inhibition concentration (IC 50 ) of drugs on the in vitro metabolism of estradiol (E2)