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Construction of NF-κB-targeting RNAi adenovirus vector and the effect of NF-κB pathway on proliferation and apoptosis of vascular endothelial cells

✍ Scribed by Gang Chen; Yufang Qiao; Jin Yao; Qiqin Jiang; Xu Lin; Feng Chen; Fenghui Lin; Miao Lin; Lixiang Lin; Pengli Zhu


Publisher
Springer
Year
2010
Tongue
English
Weight
341 KB
Volume
38
Category
Article
ISSN
0301-4851

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## Abstract Apoptosis is an endogenous process that can be a useful anti‐cancer tool. This study aimed to investigate the effect of Cl‐IB‐MECA, adenosine receptor A3 agonist, on TRAIL‐induced apoptosis of thyroid carcinoma cells. Cl‐IB‐MECA enhanced TRAIL‐mediated apoptosis in FRO but not in ARO ce