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Construction of Fused Polycyclic Ethers by Strategies Involving Ring-Closing Metathesis

โœ Scribed by J. Stephen Clark


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

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Neurotoxic marine polycyclic ethers of the brevetoxin and ciguatoxin family continue to be interesting synthetic targets as a consequence of their architectural complexity and potent biological activity. [1] They constitute a major challenge in terms of medium-size ring construction as illustrated b