Construction of four double gene substitution human × bovine rotavirus reassortant vaccine candidates: Each bears two outer capsid human rotavirus genes, one encoding P serotype 1A and the other encoding G serotype 1, 2, 3, or 4 specificity

✍ Scribed by Hoshino, Yasutaka; Jones, Ronald W.; Chanock, Robert M.; Kapikian, Albert Z.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 340 KB
• Volume: 51
• Category: Article
• ISSN: 0146-6615
• DOI: 10.1002/(sici)1096-9071(199704)51:4<319::aid-jmv10>3.0.co;2-d

✦ Synopsis

Previously, four human × bovine rotavirus reassortant candidate vaccines, each of which derived ten genes from bovine rotavirus UK strain and only the outer capsid protein VP7-gene from human rotavirus strain D (G serotype 1), DS-1 (G serotype 2), P (G serotype 3), or ST3 (G serotype 4), were developed