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Construction of collagen II/hyaluronate/chondroitin-6-sulfate tri-copolymer scaffold for nucleus pulposus tissue engineering and preliminary analysis of its physico-chemical properties and biocompatibility

✍ Scribed by Chang-qing Li; Bo Huang; Gang Luo; Chuan-zhi Zhang; Ying Zhuang; Yue Zhou

Book ID: 106400269
Publisher: Springer
Year: 2009
Tongue: English
Weight: 587 KB
Volume: 21
Category: Article
ISSN: 0957-4530
DOI: 10.1007/s10856-009-3871-5

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Collagen II/hyaluronan/chondroitin-6-sul

Collagen II/hyaluronan/chondroitin-6-sulfate tri-copolymer scaffold for nucleus pulposus tissue engineering

✍ Bo Huang; Chang-Qing Li; Yue Zhou; Gang Luo; Chuan-Zhi Zhang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 439 KB

## Abstract This study aims to investigate the bioactivity of collagen II/hyaluronan/chondroitin‐6‐sulfate tri‐copolymer as bionic scaffold for nucleus pulposus (NP) tissue engineering. Collagen II (C II) (pH 1–2) was mixed with hyaluronan (HyA) and lyophilized to prepare C II/HyA matrices. Chondro