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Construction of an infectious clone of canine herpesvirus genome as a bacterial artificial chromosome

โœ Scribed by Jun Arii; Orkash Hushur; Kentaro Kato; Yasushi Kawaguchi; Yukinobu Tohya; Hiroomi Akashi


Book ID
108209981
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
437 KB
Volume
8
Category
Article
ISSN
1286-4579

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Cloning of herpesviral genomes as bacter
โœ Heiko Adler; Martin Messerle; Ulrich H. Koszinowski ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 314 KB

Herpesviruses, which are important pathogens for both animals and humans, have large and complex genomes with a coding capacity for up to 225 open reading frames (ORFs). Due to the large genome size and the slow replication kinetics in vitro of some herpesviruses, mutagenesis of viral genes in the c