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Construction of an enantiomerically pure cis-fused 7-oxabicyclo[4.3.0]nonan-3-one skeleton. Synthesis of (1S,6R,8R,9R)-8,9-(isopropylidenedioxy)-7-oxabicyclo[4.3.0]nonan-3-one from D-allose

✍ Scribed by Tadano, Kinichi; Miyazaki, Masayuki; Ogawa, Seiichiro; Suami, Tetsuo


Book ID
126323518
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
554 KB
Volume
53
Category
Article
ISSN
0022-3263

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Enzymes in Organic Synthesis, 8. Synthes
✍ Weidner, Judith ;Theil, Fritz ;Kunath, Annamarie ;Schick, Hans πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 271 KB

## Abstract Lipase Amano PS is a suitable biocatalyst for the highly regio‐ and enantioselective transesterification of the racemic prostaglandin building block (1__S__~\*~,5__R__\*,6__R__\*,7__R__\*)‐(Β±)‐7‐hydroxy‐6‐hydroxymethyl‐2‐oxabicyclo[3.3.0]octan‐3‐one (__rac__‐1) yielding (1__S__,5__R__,6