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Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association

✍ Scribed by Miyake, Kazuaki; Yang, Woosung; Hara, Kazuo; Yasuda, Kazuki; Horikawa, Yukio; Osawa, Haruhiko; Furuta, Hiroto; Ng, Maggie CY; Hirota, Yushi; Mori, Hiroyuki

Book ID
111931586
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
165 KB
Volume
54
Category
Article
ISSN
1435-232X

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Type 2 (non-insulin-dependent) diabetes
Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family
✍ F. Shimada; H. Makino; N. Hashimoto; M. Taira; S. Seino; G. I. Bell; A. Kanatsuk πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 803 KB

Mutations were screened for in the glucokinase gene of 25 Japanese patients with Type 2 (non-insulin-dependent) diabetes mellitus. Each exon was scanned by electrophoresis of enzymatically amplified DNA segments under non-denaturing conditions and variants were sequenced. A variant pattern was detec