Construction of a novel promoter-probe vector and its application for screening strong promoter forBrevibacterium flavummetabolic engineering

A convenient plasmid system for construc

A convenient plasmid system for construction of helper-dependent adenoviral vectors and its application for analysis of the breast-cancer-specific mammaglobin promoter

✍ Chang-Xin Shi; Frank L. Graham; Mary M. Hitt 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract ## Background Helper‐dependent (HD) adenovirus (Ad) vectors, deleted of all viral coding sequences, have a higher cloning capacity, improved performance of tissue‐specific promoters, and reduced toxicity in animals relative to first‐generation Ad vectors, making these vectors promising