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Construction of a High-Resolution Linkage Map for Xp22.1-p22.2 and Refinement of the Genetic Localization of the Coffin-Lowry Syndrome Gene

✍ Scribed by Valerie Biancalana; Elisabeth Trivier; Chantal Weber; Jean Weissenbach; Peter S.N. Rowe; Jeffrey L.H. O'Riordan; Michael W. Partington; Sandra Heyberger; Claudine Oudet; Andre Hanauer


Book ID
115612288
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
561 KB
Volume
22
Category
Article
ISSN
0888-7543

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A detailed map of genetic markers was constructed around the gene for the X-linked mental retardation syndrome of BΓΆrjeson-Forssman-Lehmann (BFLS). A multipoint linkage map of framework markers across Xq26-27, based on CEPH families, was integrated with the physical map, based on a YAC contig, to co