Construction of a Chiral Quaternary Carbon Center by Indium-Catalyzed Asymmetric α-Alkenylation of β-Ketoesters
✍ Scribed by Fujimoto, Taisuke; Endo, Kohei; Tsuji, Hayato; Nakamura, Masaharu; Nakamura, Eiichi
- Book ID
- 127188457
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 88 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0002-7863
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## Abstract Diastereomeric reduction of nonactivated, hindered β‐keto and chiral β‐iminoesters are described. The influence of a α‐stereocontrolled center on the efficiency and stereoselectivity of the reduction was studied. Reaction conditions were optimized to synthesize β‐hydroxy‐ and β‐aminoest
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A novel asymmetric oxazoline ketenimine rearrangement has been observed to construct et-quaternary substituted ketones. Levels of asymmetric induction in the ketones, of up to 87% ee, were observed for this unusual rearrangement.
## Abstract For Abstract see ChemInform Abstract in Full Text.