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Construction, expression and characterization of a murine/human chimeric antibody with specificity for hepatitis B surface antigen

✍ Scribed by Yi-Wan Li; Dawson K. Lawrie; Pallaiah Thammana; Gordon P. Moore; Clyde W. Shearman


Book ID
118384325
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
1007 KB
Volume
27
Category
Article
ISSN
0161-5890

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The Fab fragment was cloned from the monoclonal cell line TAPC301-CL4, which was produced using the Epstein-Barr virus (EBV) transformation method. This cell line produces a human monoclonal antibody (CL4MAb) against the hepatitis B surface antigen (HBsAg). This MAb was shown to have hepatitis B vir