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Construction and Serological Characterization of a Recombinant Human Single Chain T-Cell Receptor

✍ Scribed by D.F. Lake; R.M. Bernstein; E.M. Hersh; H. Kaymaz; S.F. Schluter; J.J. Marchalonis

Book ID
115574906
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
477 KB
Volume
201
Category
Article
ISSN
0006-291X

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## Abstract Fusion constructs targeting tumor cells have significant potential applications against both solid tumors and hematologic malignancies. We developed a fusion construct of tumor necrosis factor (TNF) and a single‐chain antibody (scFvMEL) recognizing the gp240 antigen on human melanoma ce