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Construction and molecular characterization of mouse single-chain variable fragment antibodies against Burkholderia mallei and Burkholderia pseudomallei

โœ Scribed by Ho San Kim; Shien Tsai; Nianxiang Zou; Shyh-Ching Lo; Douglas J. Wear; Mina J. Izadjoo


Book ID
113717920
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
832 KB
Volume
365
Category
Article
ISSN
0022-1759

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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody โ€“ directed enzyme-prodrug