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Construction and identification of the helper plasmids for reverse genetic system of rabies virus street strain

✍ Scribed by Ping-gang Ming; Ying Huang; Qing Tang; Jia-liang Du; Xiao-yan Tao; Jia-xin Yan; Rong-liang Hu


Book ID
107636048
Publisher
SP Wuhan Institute of Virology, CAS
Year
2009
Tongue
English
Weight
475 KB
Volume
24
Category
Article
ISSN
1674-0769

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## Abstract ## Background Helper‐dependent (HD) adenovirus (Ad) vectors, deleted of all viral coding sequences, have a higher cloning capacity, improved performance of tissue‐specific promoters, and reduced toxicity in animals relative to first‐generation Ad vectors, making these vectors promising