Construction and humoral immune response of Epstein-Barr virus latent membrane protein 2 DNA vaccine in mice
β Scribed by Pan, Jianqing ;Zhang, Qin ;Wang, Daowen
- Book ID
- 107472353
- Publisher
- Higher Education Press and Springer
- Year
- 2009
- Tongue
- English
- Weight
- 478 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1673-7342
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## Abstract A large group of juvenile Hodgkin's disease patients (nβ=β242, mean age 11.7 years, 75% [nβ=β181] seropositive) was evaluated for antiβEpsteinβBarr virus (EBV) antibody responses and the presence of EBVβencoded EBERβRNA and latent membrane proteinβ1 (LMP1)βprotein expression in the tumo
Ten synthetic peptides containing 18-22 residues deduced from the amino-acid sequences of the EBV-encoded latentinfection-associated membrane protein (LMP) and the 2 principal nuclear antigens, EBNA-I and EBNA-2, were tested for their ability to induce lymphokine release from sensitized Tcells of EB