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Construction and expression of a polycistronic plasmid encoding N-acetylglucosamine 2-epimerase and N-acetylneuraminic acid lyase simultaneously for production of N-acetylneuraminic acid

✍ Scribed by Sun, Wujin; Ji, Wenyan; Li, Nan; Tong, Peng; Cheng, Jian; He, Ying; Chen, Yong; Chen, Xiaochun; Wu, Jinglan; Ouyang, Pingkai; Xie, Jingjing; Ying, Hanjie


Book ID
122703122
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
522 KB
Volume
130
Category
Article
ISSN
0960-8524

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It is well known that naturally occurring sialo compounds such as glycoproteins and glycolipids in cell membranes, which play important roles in biological systems'-', contain sialic acids in a-glycosidic linkage. Therefore, a facile, a-selective synthesis of sialic-acid glycosides is very important