Tumour therapy with vinca alkaloids targ
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J. R. F. Corvalan; W. Smith; V. A. Gore
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Article
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1988
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John Wiley and Sons
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French
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The functional properties of a hybrid-hybrid monoclonal antibody (MAb) recognising both CEA and Vinca alkaloids have been explored in vivo in nude mice xenografted with MAWI, a human colorectal turnour. The hybrid-hybrid MAb localises specifically onto CEA-expressing tumour tissue and, furthermore,