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Construction and characterisation of a hybrid-hybrid monoclonal antibody recognising both carcinoembryonic antigen (CEA) and vinca alkaloids

โœ Scribed by J. R. F. Corvalan; W. Smith


Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
568 KB
Volume
24
Category
Article
ISSN
0340-7004

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Tumour therapy with vinca alkaloids targ
โœ J. R. F. Corvalan; W. Smith; V. A. Gore ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 356 KB

The functional properties of a hybrid-hybrid monoclonal antibody (MAb) recognising both CEA and Vinca alkaloids have been explored in vivo in nude mice xenografted with MAWI, a human colorectal turnour. The hybrid-hybrid MAb localises specifically onto CEA-expressing tumour tissue and, furthermore,