Systematic optimization of a lead-struct
✍
Dirk Weber; Claudia Berger; Timo Heinrich; Peter Eickelmann; Jochen Antel; Horst
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
English
⚖ 279 KB
The orphan receptor, human bombesin receptor subtype 3 (BRS-3) was assigned to the G-protein coupled bombesin receptor family because of its high sequence homology with the neuromedin B receptor (NMB-R) and gastrin-releasing peptide receptor (GRP-R). Since its pharmacology is stiIl unknown, new high