The p53 homologue p63 is essential for ectodermal differentiation, such that p63؊/؊ mice lack all squamous epithelia and teeth. The p63 gene expresses at least 6 different transcripts, but information regarding the expression, regulation and function of the different isoforms has remained sparse, du
✦ LIBER ✦
Constitutive expression of ΔN-p63α isoform in human thymus and thymic epithelial tumours
✍ Scribed by Marco Chilosi; Alberto Zamò; Antonietta Brighenti; Giorgio Malpeli; Licia Montagna; Paola Piccoli; Serena Pedron; Maurizio Lestani; Giorgio Inghirami; Aldo Scarpa; Claudio Doglioni; Fabio Menestrina
- Book ID
- 106116949
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 686 KB
- Volume
- 443
- Category
- Article
- ISSN
- 1432-2307
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## Abstract Cytokines and adhesion receptors are key mediators in the dialog occurring between thymic epithelial cells (TEC) and thymocytes and regulating T cell maturation and epithelial embryonic differentiation. Among cytokines, IL‐6 can be critical in the thymus, fostering proliferation, differ