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Constitutive Expression of MC1R in HaCaT Keratinocytes Inhibits Basal and UVB-induced TNF-α Production

✍ Scribed by Geneviève Garcin; Lionel Le Gallic; Pierre-Emmanuel Stoebner; Anne Guezennec; Joelle Guesnet; Thierry Lavabre-Bertrand; Jean Martinez; Laurent Meunier

Book ID
111413454
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
494 KB
Volume
85
Category
Article
ISSN
0031-8655

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✍ Pauline Henri; Sylvain Beaumel; Anne Guezennec; Carine Poumès; Pierre-Emmanuel S 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 406 KB

## Abstract Ultraviolet A (UVA) radiations are responsible for deleterious effects, mainly due to reactive oxygen species (ROS) production. Alpha‐melanocyte stimulating hormone (α‐MSH) binds to melanocortin‐1 receptor (MC1R) in melanocytes to stimulate pigmentation and modulate cutaneous inflammato