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Constitutive and ligand-induced nuclear localization of oxytocin receptor

✍ Scribed by Conan G. Kinsey; Gianni Bussolati; Martino Bosco; Tadashi Kimura; Marie C. Pizzorno; Mitchell I. Chernin; Paola Cassoni; Josef F. Novak

Book ID
114778216
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2007
Tongue
English
Weight
627 KB
Volume
11
Category
Article
ISSN
1582-1838

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Constitutive activity and ligand-depende
Constitutive activity and ligand-dependent activation of the nuclear receptor CARβ€”insights from molecular dynamics simulations
✍ BjΓΆrn WindshΓΌgel; Antti Poso πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 434 KB

## Abstract The constitutive androstane receptor (CAR) possesses, unlike most other nuclear receptors, a pronounced basal activity __in vitro__ whose structural basis is still not fully understood. Using comparative molecular dynamics simulations of CAR X‐ray crystal structures, we evaluated the mo