Constitutive and cytokine-induced production of interleukin-6 by human myoblasts
β Scribed by Emanuela Bartoccioni; Dorothea Michaelis; Reinhard Hohlfeld
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 347 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0165-2478
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The constitutive and lipopolysaccharide (LPS)-induced secretion of interleukin 1 (IL 1) by cultured human monocytes and macrophages has been studied. Both freshly obtained monocytes and their culture-derived macrophages were induced by LPS to secrete similar amounts of IL 1. Such induction, however,
## Abstract ## Objective To determine the cellular mediators of antigenβinduced arthritis (AIA) and the relative contribution of members of the interleukinβ6 (ILβ6) family and tumor necrosis factor (TNF) in AIA. ## Methods AIA was induced in mice deficient in T and B lymphocytes, ILβ6 (ILβ6^β/β^