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Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice

✍ Scribed by Dang, Thao P; Eichenberger, Shannon; Gonzalez, Adriana; Olson, Sandra; Carbone, David P


Book ID
110067348
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
949 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract Inhibitor of differentiation‐1 (Id‐1) has been shown to play an essential role in cell proliferation, invasion, migration, and anti‐apoptosis. However, the effect of Id‐1 in mammary gland development remains unknown. Here, we generated MMTV‐Id‐1 transgenic mice to study the role of Id‐1