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Constitutional trisomy 8 mosaicism: Mechanism of origin, phenotype variability, and risk of malignancies

โœ Scribed by Danesino, Cesare; Pasquali, Francesco; Dellavecchia, Claudia; Maserati, Emanuela; Minelli, Antonella; Seghezzi, Laura


Book ID
101209976
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
2 KB
Volume
80
Category
Article
ISSN
0148-7299

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Prenatal diagnosis of mosaic trisomy 8 w
โœ A. L. Webb; J. Wolstenholme; J. Evans; S. Macphail; J. Goodship ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 159 KB

A case of trisomy 8 mosaicism, which presented at obstetric ultrasound at 18 weeks' gestation with a distended bladder and absence of amniotic fluid, is described. Analysis of DNA microsatellite polymorphisms indicates that the trisomic cell line most likely arose as the result of a post-fertilizati