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Constitutional alterations of 9p23-24 in independentBRCA2breast cancer families

✍ Scribed by M Schwab, L Savelyeva, A Claas, H An, S Brouwers

Book ID
120700560
Publisher
BioMed Central
Year
2000
Tongue
English
Weight
298 KB
Volume
2
Category
Article
ISSN
1465-5411

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Retention of polysomy at 9p23–24 during
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✍ Larissa Savelyeva; Andreas Claas; Hanxiang An; Ruthild G. Weber; Peter Lichter; πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 434 KB

Somatic genetic alterations of 9p have been seen in a wide range of human cancers, including breast cancer. Loss of heterozygosity analysis of primary breast cancer tumors has revealed a high frequency of deletion of DNA from 9p21-22 encompassing the MTS1 (P16/CDKN2A) gene. We report the approximate