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Constant fed-batch culture of methanol-utilizing corynebacterium producing vitamin B 12

✍ Scribed by M. Andriantsoa; M. Laget; A. Cremieux; G. Dumenil


Publisher
Springer Netherlands
Year
1984
Tongue
English
Weight
252 KB
Volume
6
Category
Article
ISSN
0141-5492

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✦ Synopsis


SUWtRY.

A fed-batch culture of methanol-utilizing microorganism (Corynebacterim sp. XG), a vitamin B 12 producer, was carried out with constant feed of substrate. Experimental results agreed with the theorical model proposed in the literature. Using this feeding system, the final biomass and vitamin B 12 concentration reached 16.3 g/l and 88O,ug/l respectively after a 53 h incubation period at 30°C.