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Consistent occurrence of a 19p+ marker chromosome and loss of 11p material in ovarian seropapillary cystadenocarcinomas

✍ Scribed by Dr. Tanja Pejovic; Sverre Heim; Nils Mandahl; Bengt Elmfors; Ulla-Maria Flodérus; Stefan Furgyik; Göran Helm; Helena Willén; Felix Mitelman


Book ID
102220751
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
477 KB
Volume
1
Category
Article
ISSN
1045-2257

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✦ Synopsis


Cytogenetic analysis of short-term cultures from I I moderately to poorly differentiated ovarian seropapillary cystadenocarcinomas revealed clonal chromosomal abnormalities in nine tumors. Two bands were involved in structural rearrangements in more than half of the tumors. The band most frequently affected was I9p I 3; rearrangements giving rise to a I9p+ marker chromosome were found in seven tumors, and in four of them the 19p+ markers appeared to be identical. Structural rearrangements resulting in loss of I I p 13-I I pter material were found in six tumors.


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