The patched polymorphism Pro1315Leu (C39
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Jenny Chang-Claude; Alison Dunning; Udo Schnitzbauer; Petra Galmbacher; Louise T
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Article
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2003
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John Wiley and Sons
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French
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## Abstract The gene coding for the human homologue of the __Drosophila__ segment polarity gene __patched__ (PTCH1) is mutated in several common human tumors. In mice, haplodeficiency at the __Ptch1__ locus results in severe histologic defects in mammary ductal structure. We found no mutations with