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Conservation of alternative polyadenylation patterns in mammalian genes

โœ Scribed by Takeshi Ara; Fabrice Lopez; William Ritchie; Philippe Benech; Daniel Gautheret

Book ID
115003976
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
314 KB
Volume
7
Category
Article
ISSN
1471-2164

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## Abstract A set of mutated SV40 early polyadenylation signals (SV40pA) with varying strengths is generated by mutating the AATAAA sequence in the wildโ€type SV40pA. They are shown to control the expression level of a gene over a 10โ€fold range using luciferase reporter genes in transient transfecti