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Consequences of regulated pre-mRNA splicing in the immune system

✍ Scribed by Lynch, Kristen W.

Book ID
109954753
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
231 KB
Volume
4
Category
Article
ISSN
1474-1741

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Nuclear pre-mRNAs must be precisely processed to give rise to mature cytoplasmic mRNAs. This maturation process, known as splicing, involves excision of intron sequences and ligation of the exon sequences. One of the major problems in understanding this process is how splice sites, the sequences whi