The optimal and safer interleukin-2 (IL-2) dose for treatment of chronic hepatitis C virus (HCV) infection has been studied in 33 HCV-RNA positive patients with chronic hepatitis C. Patients were randomly allocated to receive 5 days per week during 12 weeks IL-2 doses of: 0.9 MIU (n = 10), 1.8 MIU (
Consequences of chronic hepatitis C: A review article for the hematologist
โ Scribed by Dr. Louis M. Aledort
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 901 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
The hepatitis C virus (HCV) has been cloned, and assays capable of detecting antibody to HCV recombinant proteins (antiโHCV) have been developed. Concurrent with the cloning and development of the antiโHCV screening tests, trials with interferon alfaโ2b have documented biochemical and histologic improvement in the indices of hepatitis C and nonโA, nonโB (NANB) in patients who were chronically infected. Subsequently, the antiโHCV assays and interferon alfaโ2b have become clinically available. These new detection and treatment modalities can now be used in the management of hemophilics and other chronically transfused patients who bear great risk for bloodโborne infections and manifest signs of chronic hepatitis. ยฉ 1993 WileyโLiss, Inc.
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