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Consecutive phase II trials of docetaxel (taxotere®) 100 MG/M2 and 75 MG/M2 with prednisone in patients with stage IIIB and IV non-small cell lung cancer

Book ID
122939649
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
145 KB
Volume
11
Category
Article
ISSN
0169-5002

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Phase II trial of a 75-mg/m2 dose of doc
Phase II trial of a 75-mg/m2 dose of docetaxel with prednisone premedication for patients with advanced non-small cell lung cancer
✍ Vincent A. Miller; James R. Rigas; Prudence A. Francis; Stefan C. Grant; Katheri 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 493 KB 👁 2 views

## Background. A prior Phase I1 study of a 100-mg/m2 dose of docetaxel conducted at the Memorial Sloan-Kettering Cancer Center (New York, NY) demonstrated a 38% response rate with grade 3 or 4 neutropenia in 76% of the patients and a grade 2 or greater rash or infusionrelated reaction in 41% and 3