Consecutive Michael-addition-olefination sequences with Cr(CO)3-complexed aryl allenylphosphonates — An efficient synthesis of heterocyclic substituted arene complexes

✍ Scribed by Thomas J.J. Müller; Markus Ansorge

• Book ID: 104208302
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 608 KB
• Volume: 54
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(97)10381-7

✦ Synopsis

The Michael-Addition of 1,2 and 1,3-difunctional carbonyl compounds 6 to Cr(CO)3complexed aryl allenylphosphonates 5 followed by an intramolecular Horner-Emmons-Wadsworth olefination in boiling THF gives rise to arene Cr(CO)3 substituted heterocycles 7 in moderate to good yields.