Connexin43 pseudogene is expressed in tumor cells and inhibits growth
β Scribed by Kandouz, Mustapha; Bier, Andrew; Carystinos, George D; Alaoui-Jamali, Moulay A; Batist, Gerald
- Book ID
- 110068581
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 281 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
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Many lines of evidence support the hypothesis that connexins form a family of tumor-suppressor genes. Transfection of connexin43 (Cx43) into rat C6 glioma cells have revealed that Cx43 functions as a growth-and tumor-suppressor in C6 cells. In previous studies, we and others have reported that sever
The immunohistochemical distribution and ultrastructural immunolocalization of con-nexin43 (Cx43) in the neural retina of the rabbit was investigated. Cx43 immunolabeling appeared in the form of distinct puncta distributed on different kinds of glial cells and exclusively in the myelinated fiber reg