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Connexin 26 gene linked to a dominant deafness

✍ Scribed by Denoyelle, Françoise; Lina-Granade, Genevieve; Plauchu, Henri; Bruzzone, Roberto; Chaïb, Hassan; Lévi-Acobas, Fabienne; Weil, Dominique; Petit, Christine


Book ID
109732792
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
202 KB
Volume
393
Category
Article
ISSN
0028-0836

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Absence of deafness-associated connexin-
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We have investigated the prevalence of mutations in the connexin 26 (GJB2) gene in Omani population using both PCR-RFLP and direct DNA sequencing methods. Two common GJB2 gene mutations (35delG and 167delT) were screened in 280 healthy controls and 95 deaf patients using two different PCR-RFLP metho