In this study, virtually all sulfated glycosaminoglycan (GAG) synthesized and secreted by human synovial cells, both normal and rheumatoid, was detected in the form of proteoglycans of monomeric size. Enzyme hydrolysis studies that were performed demonstrated dermatan sulfate to be the dominant GAG
Connective tissue activation
β Scribed by Michael A. Gordon; Morley D. Hollenberg; C. William Castor
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 734 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0004-3591
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## Abstract Connective tissue __a__ctivating __p__eptides from lymphocytes (CTAPβI) and platelets (CTAPβIII) are known to stimulate glycosaminoglycan synthesis, glycolysis, and mitogenesis in connective tissue cell cultures. Direct evidence suggested that increased accumulation of cyclic AMP was in