Connections between average and individual bioequivalence
โ Scribed by Axel Munk
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 156 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0277-6715
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A bootstrap-type hypothesis test procedure for assessing individual (or population) bioequivalence between two drug formulations is suggested in a draft guidance from the United States Food and Drug Administration (FDA). The purpose of this article is to study the unknown properties of this test pro
Evaluation of equivalence of two formulations of a drug typically entails the comparison of average bioavailabilities. Recently, however, authors have become aware that this may be insufficient to assess individual bioequivalence, that is, interchangeability of formulations on an individual basis. T
## Abstract The average distance ยต(__G__) of a connected graph __G__ of order __n__ is the average of the distances between all pairs of vertices of __G__, i.e., $\mu(G)=\left(\_{2}^{n}\right)^{-1}\sum\_{\{x,y\}\subset V(G)}d\_{G} (x,y)$, where __V__(__G__) denotes the vertex set of __G__ and __d_