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Conjugation of benzoic acid with glycine in human liver and kidney: a study on the interindividual variability

✍ Scribed by Temellini, A.; Mogavero, S.; Giulianotti, P. C.; Pietrabissa, A.; Mosca, F.; Pacifici, G. M.


Book ID
118734158
Publisher
Informa plc
Year
1993
Tongue
English
Weight
437 KB
Volume
23
Category
Article
ISSN
0049-8254

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The major route of biotransformation of benzoic acid and salicylic acid in man is conjugation with glycine, resulting in the formation of hippuric acid and salicyluric acid, respectively. Both processes are capacity-limited in the usual dose range and approach a maximum rate following administration