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Conjugation of an Antisense Oligodeoxynucleotide to Ribonuclease H Results in Sequence-Specific Cleavage and Intracellular Inhibition of HCV Gene Expression

✍ Scribed by Fukuma, Toshiko; Walton, Cherie M.; Wu, Catherine H.; Wu, George Y.

Book ID: 126848796
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 160 KB
Volume: 14
Category: Article
ISSN: 1043-1802
DOI: 10.1021/bc0256300

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Sequence-specific cleavage of HCV RNA by

Sequence-specific cleavage of HCV RNA by the modified ribonuclease H conjugated to HCV antisense oligodeoxynucleotides: Toshiko Fukuma, Cherie M Walton, University of Connecticut School of Medicine, Farmington, CT; Catherine H Wu, University of Connecticut School of Medicine, Farmington, CT; George Y Wu, University of Connectivity School of Medicine, Farmington, CT

📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB