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Conjugates of Bisphosphonates with Derivatives of Ursolic, Betulonic, and Betulinic Acids

✍ Scribed by Bekker, K. S.; Chukanov, N. V.; Popov, S. A.; Grigor’ev, I. A.

Book ID
120635497
Publisher
Springer
Year
2013
Tongue
English
Weight
51 KB
Volume
49
Category
Article
ISSN
0009-3130

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✍ Oxana B. Kazakova; Gul’nara V. Giniyatullina; Emil Yu. Yamansarov; Genrikh A. To 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 187 KB

The synthesis of new betulin and ursolic acid derivatives and evaluation of their antiviral activity in vitro is reported. Betulin was modified at positions C-3, C-20 and C-28 to afford the derivatives with nicotinoyl-, methoxycynnamoyl-, alkyne and aminopropoxy-2-cyanoethyl-moieties. The two stage